Revolution in Respiratory Care: Aptar Pharma’s Expertise in Inhalation Drug Delivery

In the realm of modern medicine, Inhaler devices stands as a vital and innovative approach to treating respiratory conditions. Aptar Pharma, a leader in this field, provides comprehensive support for the development of inhalation drug delivery products, from early-stage formulation to finished product release. This article explores the breadth of Aptar Pharma’s capabilities and the benefits of their advanced inhalation devices.

Why Inhalation Drug Delivery Matters

Inhalation drug delivery is essential for treating respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease (COPD). The direct delivery of medication to the lungs ensures quick and effective relief, making it a preferred method for patients and healthcare providers. Let’s delve into the specifics of why this method is so critical.

Benefits of Inhalation Drug Delivery

  1. Rapid Onset of Action: Inhalation allows the medication to reach the lungs quickly, providing almost immediate relief from symptoms.
  2. Reduced Systemic Side Effects: Since the drug is delivered directly to the lungs, there is less systemic absorption, which means fewer side effects compared to oral or injectable medications.
  3. Higher Local Concentration: Inhaled medications can achieve higher local concentrations in the lungs, which is especially beneficial for treating respiratory conditions.

Aptar Pharma’s Expertise in Inhalation Devices

Aptar Pharma excels in creating state-of-the-art inhalation devices tailored to meet the needs of patients and healthcare providers. Their extensive range includes pressurized metered dose inhalers (pMDIs), breath-actuated inhalers (BAIs), and dry powder inhalers (DPIs).

Pressurized Metered Dose Inhalers (pMDIs)

The pMDI is a popular device due to its reliability and ease of use. Aptar Pharma’s DF30 metering valve platform is a standout in this category, offering consistent and precise dosing. This platform has been integral to many successful asthma and COPD treatments.

Breath Actuated Inhalers (BAIs)

BAIs are designed to release medication when the patient inhales, ensuring proper drug delivery without the need for coordination between actuation and inhalation. This makes them particularly beneficial for patients who may have difficulty using traditional pMDIs.

Dry Powder Inhalers (DPIs)

DPIs, such as Aptar Pharma’s Orbital™ and Prohaler® systems, provide a solution for delivering powdered formulations. These devices are especially useful for delivering high-payload drugs and ensuring patient adherence, critical for managing chronic conditions.

Innovation at the Forefront: The Orbital™ and PureHale® Systems

Orbital™ DPI

The Orbital™ DPI represents a leap forward in inhalation technology. It delivers high-payload powder drugs directly to the lungs, offering a flexible, hand-held device that adapts to various formulations. This innovation ensures that patients receive the correct dosage efficiently and effectively.

PureHale® System

The PureHale® system is a first-of-its-kind, ready-to-use nebulizer-like device. It delivers a fine mist of saline or natural ingredient formulations to alleviate upper respiratory symptoms. This system is particularly useful for patients seeking a non-pharmaceutical option for symptom relief.

Ensuring Patient Adherence

Aptar Pharma understands the importance of patient adherence in the treatment of chronic respiratory conditions. Their Prohaler® system is a pre-metered multi-dose DPI designed to encourage consistent use by providing a reliable and easy-to-use device.

Training and Education

To support patients and healthcare providers, Aptar Pharma offers training devices that allow practice and familiarization with inhalation techniques. This ensures that users can confidently operate their inhalers when it matters most.

Regulatory Expertise for OINDP Products

Navigating the regulatory landscape for Orally Inhaled and Nasal Drug Products (OINDP) can be complex. Aptar Pharma brings substantial regulatory expertise to every project, supporting customers from development to market launch.

Comprehensive Regulatory Support

Aptar Pharma’s regulatory support teams have a wealth of experience and data, ensuring that all regulatory requirements are met. This includes support for sustainable pMDIs and other asthma inhalers, addressing the growing need for environmentally friendly options.

Unrivalled Metering Valve Data

With over 25 years of experience, Aptar Pharma’s DF30 metering valves have been incorporated into major OINDP products. This extensive history allows them to provide robust metering valve data to support regulatory submissions and continuous improvement.

Tips for Choosing the Right Inhaler Device

Selecting the appropriate inhaler device is crucial for effective treatment. Here are some tips to help healthcare providers and patients make the best choice:

  1. Assess Patient Needs: Consider the patient’s ability to use the device correctly. For example, BAIs are ideal for those who struggle with coordination.
  2. Evaluate Drug Formulation: Some drugs are better suited for DPIs, while others are more effective when delivered via pMDIs.
  3. Consider Adherence: Devices that are easy to use and maintain, like the Prohaler®, can improve patient adherence.
  4. Environmental Impact: For environmentally conscious patients, sustainable inhaler options should be considered.


Inhalation drug delivery is a cornerstone of modern respiratory treatment, offering rapid relief and targeted medication delivery. Aptar Pharma stands out as a leader in this field, providing innovative devices and comprehensive support to ensure successful treatment outcomes. Whether it’s through their advanced pMDIs, DPIs, or their cutting-edge Orbital™ and PureHale® systems, Aptar Pharma is dedicated to improving the lives of patients with respiratory conditions.

By understanding the benefits of inhalation drug delivery and the capabilities of Aptar Pharma, healthcare providers and patients can make informed decisions to achieve optimal respiratory health. With their regulatory expertise and commitment to innovation, Aptar Pharma continues to be a trusted partner in the journey towards better respiratory care.